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Our analyses illustrate the wide spectrum of disease trajectories as shown by differences
in incidence, survival, and clinical pathways. We have provided a modular analytical
framework that can be used to monitor the impact of the pandemic and generate evidence
of clinical and policy relevance using multiple EHR sources.
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The COVID-19 pandemic has demanded a huge effort to identify the risks associated
with poor outcomes. The focus has been particularly relevant in patients with immune-mediated
inflammatory diseases and those on therapies that suppress the immune system. Small
early observational studies looked worrisome, but as data from larger studies became
available a consistent picture became evident. Demographic risk factors such as age
and comorbidity are really the salient factors, with some risk from underlying disease
and a few specific therapeutic agents, such as rituximab.
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The coronavirus disease (COVID-19) pandemic has created an urgent need for coordinated mechanisms to respond to the outbreak across health sectors, and digital health solutions have been identified as promising approaches to address this challenge. Thi
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In 2020, Exemplars in Global Health launched a series of short- and long-term research projects to help us understand the impact of the COVID-19 pandemic in countries and communities around the world.
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