COVID-19
Contact tracing apps are potentially useful tools for supporting national COVID-19 containment strategies. Various national apps with different technical design features have been commissioned and issued by governments worldwide.
Objective: Our goal was to develop and propose an item set that was suitable for describing and monitoring nationally issued COVID-19 contact tracing apps.
This item set could provide a framework for describing the key technical features of such apps and monitoring their use based on widely available information.
Methods: We used an open-source intelligence approach (OSINT) to access a multitude of publicly available sources and collect data and information regarding the development and use of contact tracing apps in different countries over several months (from June 2020 to January 2021). The collected documents were then iteratively analyzed via content analysis methods. During this process, an initial set of subject areas were refined into categories for evaluation (ie, coherent topics), which were then examined for individual features.
These features were paraphrased as items in the form of questions and applied to information materials from a sample of countries (ie, Brazil, China, Finland, France, Germany, Italy, Singapore, South Korea, Spain, and the United Kingdom [England and Wales]). This sample was purposefully selected; our intention was to include the apps of different countries from around the world and to propose a valid item set that can be relatively easily applied by using an OSINT approach.
Results: Our OSINT approach and subsequent analysis of the collected documents resulted in the definition of the following five main categories and associated subcategories:
(1) background information (open-source code, public information, and collaborators);
(2) purpose and workflow (secondary data use and warning process design);
(3) technical information (protocol, tracing technology, exposure notification system, and interoperability);
(4) privacy protection (the entity of trust and anonymity); and
(5) availability and use (release date and the number of downloads).
Based on this structure, a set of items that constituted the evaluation framework were specified. The application of these items to the 10 selected countries revealed differences, especially with regard to the centralization of the entity of trust and the overall transparency of the apps’ technical makeup.
Conclusions: We provide a set of criteria for monitoring and evaluating COVID-19 tracing apps that can be easily applied to publicly issued information. The application of these criteria might help governments to identify design features that promote the successful, widespread adoption of COVID-19 tracing apps among target populations and across national boundaries.
read the study at https://mhealth.jmir.org/2021/3/e27232
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Since the start of the pandemic, new technologies have been developed to help reduce the spread of the infection.
Some of the most common safety measures today include measuring a person’s temperature, covering your nose and mouth with a mask, contact tracing, disinfection, and social distancing. Many businesses have adopted various technologies, including those with artificial intelligence (AI) underneath, helping to adhere to the COVID-19 safety measures.
As an example, numerous airlines, hotels, subways, shopping malls, and other institutions are already using thermal cameras to measure an individual’s temperature before people are allowed entry. In its turn, public transport in France relies on AI-based surveillance cameras to monitor whether or not people are social-distancing or wearing masks. Another example is requiring the download of contact-tracing apps delivered by governments across the globe.
However, there are a number of issues.
While many of these solutions help to ensure that COVID-19 prevention practices are observed, many of them have flaws or limits. In this article, we will cover some of the issues creating obstacles for fighting the pandemic.
Issue #1. Manual temperature scanning is tricky
Issue #2. Monitoring crowds is even more complex
Issue #3. Contact tracing leads to privacy concerns
Issue #4. UV rays harm eyes and skin
Issue #5. UVC robots are extremely expensive
Issue #6. No integration, no compliance, no transparency
Regardless of the safety measures in place and existing issues, innovations are already playing a vital role in the fight against COVID-19. By improving on existing technology, we can make everyone safer as we all adjust to the new normal.
read the details at https://www.altoros.com/blog/whats-wrong-with-ai-tools-and-devices-preventing-covid-19/
Lire l'article complet sur : www.altoros.com
Numerous studies demonstrate frequent mutations in the genome of SARS-CoV-2. Our goal was to statistically link mutations to severe disease outcome.
We found that automated machine learning, such as the method of Tsamardinos and coworkers used here, is a versatile and effective tool to find salient features in large and noisy databases, such as the fast growing collection of SARS-CoV-2 genomes.
In this work we used machine learning techniques to select mutation signatures associated with severe SARS-CoV-2 infections. We grouped patients into 2 major categories (“mild” and “severe”) by grouping the 179 outcome designations in the GISAID database.
A protocol combined of logistic regression and feature selection algorithms revealed that mutation signatures of about twenty mutations can be used to separate the two groups. The mutation signature is in good agreement with the variants well known from previous genome sequencing studies, including Spike protein variants V1176F and S477N that co-occur with DG14G mutations and account for a large proportion of fast spreading SARS-CoV-2 variants. UTR mutations were also selected as part of the best mutation signatures. The mutations identified here are also part of previous, statistically derived mutation profiles.
An online prediction platform was set up that can assign a probabilistic measure of infection severity to SARS-CoV-2 sequences, including a qualitative index of the strength of the diagnosis. The data confirm that machine learning methods can be conveniently used to select genomic mutations associated with disease severity, but one has to be cautious that such statistical associations – like common sequence signatures, or marker fingerprints in general – are by no means causal relations, unless confirmed by experiments.
Our plans are to update the predictions server in regular time intervals. While this project was underway more than 100 thousand sequences were deposited in public databases, and importantly, new variants emerged in the UK and in South Africa that are not yet included in the current datasets. Also, in addition to mutations, we plan to include also insertions and deletions which will hopefully further improve the predictive power of the server.
The study was funded by the Hungarian Ministry for Innovation and Technology (MIT) , within the framework of the Bionic thematic programme of the Semmelweis University.
Read the entire study at https://www.biorxiv.org/content/10.1101/2021.04.01.438063v1.full
Access the online portal mentioned above at https://covidoutcome.com/
Lire l'article complet sur : www.biorxiv.org
Identifying new COVID-19 cases is challenging. Not every suspected case undergoes testing, because testing kits and other equipment are limited in many parts of the world. Yet populations increasingly use the internet to manage both home and work life during the pandemic, giving researchers mediated connections to millions of people sheltering in place.
Objective: The goal of this study was to assess the feasibility of using an online news platform to recruit volunteers willing to report COVID-19–like symptoms and behaviors.
Methods: An online epidemiologic survey captured COVID-19–related symptoms and behaviors from individuals recruited through banner ads offered through Microsoft News. Respondents indicated whether they were experiencing symptoms, whether they received COVID-19 testing, and whether they traveled outside of their local area.
Results: A total of 87,322 respondents completed the survey across a 3-week span at the end of April 2020, with 54.3% of the responses from the United States and 32.0% from Japan. Of the total respondents, 19,631 (22.3%) reported at least one symptom associated with COVID-19. Nearly two-fifths of these respondents (39.1%) reported more than one COVID-19–like symptom. Individuals who reported being tested for COVID-19 were significantly more likely to report symptoms (47.7% vs 21.5%; P<.001). Symptom reporting rates positively correlated with per capita COVID-19 testing rates (R2=0.26; P<.001). Respondents were geographically diverse, with all states and most ZIP Codes represented. More than half of the respondents from both countries were older than 50 years of age.
Conclusions: News platforms can be used to quickly recruit study participants, enabling collection of infectious disease symptoms at scale and with populations that are older than those found through social media platforms. Such platforms could enable epidemiologists and researchers to quickly assess trends in emerging infections potentially before at-risk populations present to clinics and hospitals for testing and/or treatment.
source: Credit to Regenstrief Institute
read the entire study here : https://www.jmir.org/2021/5/e24742
Lire l'article complet sur : www.jmir.org